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カタログ番号 | 製品名 | 別名 | ターゲット |
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T22234 | Alloxazine | Adenosine Receptor | |
Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor. | |||
T7021 | ZM241385 | Adenosine Receptor | |
ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor. | |||
T16140 | MRS 1754 | Adenosine Receptor | |
MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats. | |||
T14078 | AB928 | Adenosine Receptor | |
AB928 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. It has immunomodulatory activity[1]. | |||
T12161 | N6-Ethyladenosine | Adenosine Receptor | |
N6-Ethyladenosine is an adenosine derivative, acts as an agonist of Adenosine receptor(hA1AR and hA3AR with Kis of 4.9 and 4.7 nM , respectively). | |||
T8512 | BAY-545 | Adenosine Receptor | |
BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM). | |||
T6979 | SCH 58261 | SCH58261 | Adenosine Receptor |
SCH 58261 is a potent and selective A2a adenosine receptor antagonist.The Ki =2.3 nM for rat A2a and 2 nM is for bovine A2a. | |||
T8312 | Derenofylline | Adenosine Receptor | |
Derenofylline is a selective and potent adenosine A(1) antagonist in vitro (Ki=1 nM) | |||
T14944 | CGS 15943 | PI3K , Adenosine Receptor | |
CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM , respectively. | |||
T17023 | Tecadenoson | CVT-510 | Adenosine Receptor |
Tecadenoson (CVT-510) is a selective agonist of A1 adenosine receptor. | |||
TQ0125 | Capadenoson | BAY 68-4986 | Adenosine Receptor |
Capadenoson (BAY 68-4986) is a selective adenosine-A1 receptor agonist. | |||
T16136 | MRS-1706 | Adenosine Receptor | |
MRS-1706 has Ki values of 1.39, 112, 157, and 230 nM for human A2B, A2A, A1, and A3 receptors respectively. MRS-1706 is an effective and selective adenosine A2B receptor inverse agonist. | |||
T14127 | Adenosine A1 receptor activator T62 | Adenosine Receptor | |
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve... | |||
T4290 | Preladenant | SCH-420814 | Adenosine Receptor |
Preladenant (SCH-420814) is an orally bioavailable antagonist of the adenosine A2A receptor (Ki: 1.1 nM) and has >1000-fold selectivity over all other adenosine receptors. | |||
T6552 | Istradefylline | KW-6002 | Adenosine Receptor |
Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails. It has been used in trials studying the treatment and basic science of Drug Ab... | |||
T9238 | KI-7 | Adenosine Receptor | |
KI-7 is an adenosine A2B receptor positive allosteric modulator. | |||
T27076 | 8-Cyclopentyl-1,3-dimethylxanthine | CPT | Adenosine Receptor |
8-Cyclopentyl-1,3-dimethylxanthine (CPT) is a potent antagonist of adenosine A1 receptor. | |||
T16980 | Taminadenant | Adenosine Receptor | |
Taminadenant is an adenosine receptor antagonist. | |||
T12160 | N6-Cyclohexyladenosine | CHA | Adenosine Receptor |
N6-Cyclohexyladenosine (CHA) is a selective agonist of A1 receptor with EC50 of 8.2 Nm. N6-Cyclohexyladenosine exerts anticonvulsant effects and protects against neuronal death. CHA was also found to inhibit the pressor ... | |||
T7683 | Adenosine amine congener | ADAC | Adenosine Receptor |
Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,. | |||
T7340 | 5'-N-Ethylcarboxamidoadenosine | NECA | Adenosine Receptor |
5'-N-Ethylcarboxamidoadenosine (NECA) is an agonist of Adenosine receptor, increases cerebral extravasation of fluorescein and low molecular weight dextran independent of blood-brain barrier modulation. | |||
T37792 | A2A receptor antagonist 1 | CPI-444 analog,A2A receptor antagonist 1 | Adenosine Receptor |
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively. | |||
T4265 | AZD4635 | HTL1071 | Adenosine Receptor |
AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM). | |||
T0362 | Ticlopidine hydrochloride | Ticlodone,Ticlopidine HCl,Ticlodix | Adenosine Receptor |
Ticlopidine hydrochloride (Ticlodix) is an effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES. | |||
T8551 | Nitrobenzylthioinosine | NBMPR | AChR , Adenosine Receptor |
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity. | |||
T7183 | CPI-444 | V81444,ciforadenant | Adenosine Receptor |
CPI-444 (V81444) is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer. | |||
T6441 | CGS 21680 Hydrochloride | CGS 21680 HCl | Adenosine Receptor |
CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor. | |||
T6884 | Namodenoson | 2-Cl-IB-MECA,CF-102 | Adenosine Receptor |
Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist. | |||
T22744 | DPCPX | PD 116948 | Adenosine Receptor |
DPCPX (PD 116948) is an A1 adenosine receptor antagonist | |||
T2373 | Vipadenant | CEB-4520,BIIB-014 | Adenosine Receptor |
Vipadenant (CEB-4520)(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM; less potent for A1(Ki=69 nM). | |||
T2671 | Regadenoson | CVT-3146,Lexiscan | Adenosine Receptor |
Regadenoson (CVT-3146) is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine re... | |||
T7509 | PD 117519 | CI947 | Adenosine Receptor |
PD 117519 (CI947) is an agonist of adenosine receptor | |||
T7188 | Piclidenoson | CF-101,IB-MECA | Apoptosis , Adenosine Receptor |
Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients. | |||
T12163 | N6-(2-Phenylethyl)adenosine | N6-Phenethyladenosine,N6-Phenylethyladenosine | Adenosine Receptor |
T15418 | GS-6201 | CVT-6883 | Adenosine Receptor |
GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM. | |||
T21389 | Enprofylline | Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum | Others |
Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of sick... | |||
T9330 | MIPS521 | {2-Amino-4-[3,5-bis(trifluoromethyl)phenyl]thiophen-3-yl}(4-chlorophenyl)methanone | Adenosine Receptor |
MIPS521 ({2-Amino-4-[3,5-bis(trifluoromethyl)phenyl]thiophen-3-yl}(4-chlorophenyl)methanone) is a positive allosteric modulator of the A1R. | |||
T7320 | Tozadenant | SYN115 | Adenosine Receptor |
Tozadenant (SYN115) is an adenosine A2A receptor antagonist(Ki of 11.5 nM and 6 nM on human and rhesus,respectively) | |||
T1083L | Theophylline monohydrate | Quibron | HDAC , PDE , Adenosine Receptor |
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ... | |||
T23336 | SCH442416 | SCH 442416 | Adenosine Receptor |
SCH442416 (SCH 442416) is an selective antagonist of adenosine A2A receptor. SCH442416 binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). | |||
T9516 | Binodenoson | WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos | Adenosine Receptor |
Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stres... | |||
T29112 | VPC171 | VPC 171,VPC-171 | Adenosine Receptor |
VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM). | |||
T23535 | Xanthine amine congener | Adenosine Receptor | |
Xanthine amine congener is an Adenosine receptor antagonist. | |||
T37793 | A2B receptor antagonist 2 | A2B receptor antagonist 2 | Adenosine Receptor |
A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B). | |||
T35938 | D-myo-Inositol-4-phosphate (ammonium salt) | ||
D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied I... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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TN2247 | Swertisin | Adenosine Receptor | |
Swertisin, a novel herbal biomolecule, shows a strong antihyperglycemic action. Swertisin is an adenosine A1 receptor antagonist, is known to have antidiabetic, anti-inflammatory and antioxidant effects. | |||
T1681 | Aminophylline | Phyllocontin | PDE , Adenosine Receptor |
Aminophylline (Phyllocontin) is a competitive nonselective phosphodiesterase inhibitor giving a bronchodilatory effect. | |||
T0892 | Diphylline | Dyphylline,Diprophylline | PDE , Adenosine Receptor |
Diphylline (Diprophylline) is a xanthine derivative. Diphylline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Diphylline probably acts as a competitive inhibitor of phosphodies... | |||
T5940 | Proxyphylline | 7-(2-Hydroxypropyl)theophylline | PDE , Adenosine Receptor |
Proxyphylline (7-(2-Hydroxypropyl)theophylline) is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant, vasodilator and bronchodilator. | |||
T5S1895 | Norisoboldine | Laurelliptine,(+)-Laurelliptine | MAPK , Adenosine Receptor |
1. Norisoboldine ((+)-Laurelliptine) might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. 2. Norisobo... | |||
T0625 | Theobromine | 3, 7-Dimethylxanthine,3,7-Dimethylxanthine | Endogenous Metabolite , PDE , Adenosine Receptor |
Theobromine (3,7-Dimethylxanthine), a xanthine alkaloid, is used as a bronchodilator and as a vasodilator. | |||
T0480 | Doxofylline | Doxophylline | PDE , Adenosine Receptor |
Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with s... | |||
T0437 | Inosine | INO 495,NSC 20262 | ROS , Endogenous Metabolite , Adenosine Receptor |
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties. | |||
T1083 | Theophylline | Theo-24,1,3-Dimethylxanthine | Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy |
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3... | |||
T2205 | Acefylline | Theophylline-7-acetic acid,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid | TNF , PAD , PKA , HDAC , PDE , Adenosine Receptor |
Acefylline (Theophylline-7-acetic acid), a stimulant drug of the xanthine chemical class, acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation Etanautine to help... | |||
T0853L | Adenosine 5'-monophosphate monohydrate | 5'-AMP,5'-AMP monohydrate,5'-Adenylic acid | AMPK , Adenosine Receptor , HSV |
Adenosine 5'-monophosphate monohydrate (5'-AMP) , also known as 5'-adenylic acid, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid and the nucleoside adenosine. Adenosine 5'-monophospha... |